FIP Advocates and Champions

What does TDM do?

• TDM measures the plasma concentration of GS-441524 and can determine whether that concentration is within or outside (too low or too high) the likely effective therapeutic range. 

• TDM may also be used if you believe that the treatment is not progressing well or if you are considering a shorter treatment period. 

 

This FREE testing is being offered by the FIP Clinical Research Team at The Royal Dick School of Veterinary Studies, Edinburgh University.

It is available internationally – you only pay for shipping via FedEx or DHL.

They also do FREE AGP assays on all TDM samples 

 

TDM and AGP testing for FIP treatment is not currently available in Canada or the USA!

 

• TDM samples should be taken after 2-3 days of being on a particular dose 

Samples are collected at; 

1. between 3-5 hours after the last dose was administered – Peak sample 

2. between 9-11 hours after the last dose was administered – Trough sample 

Reporting time is 3 – 4 working days. 

 

We are including their latest study which has just been published: Therapeutic Drug Monitoring of GS-441524 in Cats with Feline Infectious Peritonitis: Pharmacokinetic Variability and Implications for Dose Optimization.